Acute effect of fine particulate matters on daily cardiovascular disease mortality in seven cities of China
10.3760/cma.j.issn.0254-6450.2017.03.003
- VernacularTitle:中国7个城市大气PM2.5对人群心血管疾病死亡的急性效应研究
- Author:
Ruiming LIANG
1
;
Peng YIN
;
Lijun WANG
;
Yichong LI
;
Jiangmei LIU
;
Yunning LIU
;
Jinling YOU
;
Jinlei QI
;
Maigeng ZHOU
Author Information
1. 中国疾病预防控制中心慢性非传染性疾病预防控制中心生命登记与死因监测室
- Keywords:
Fine particulates;
Cardiovascular disease;
Mortality;
Time-series
- From:
Chinese Journal of Epidemiology
2017;38(3):283-289
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of fime particulate matters with an aerodynamic diameter less than 2.5 μtm (PM2.5) on daily cardiovascular disease mortality in seven cities of China.Methods Daily average concentrations of PM2.5,cardiovascular disease mortality data and environmental data were collected from January 1,2013 to December 31,2015 in seven cities of China,including Shijiazhuang,Haerbin,Shanghai,Wuhan,Guangzhou,Chengdu and Xi'an.We linked generalized additive model with Quasi-Poisson distribution to evaluate the association between daily concentrations of PM2.5 and cardiovascular disease mortality at single-city level and multi-city level,after adjusting for the long-term and seasonal trend,as well as meteorological factors and the effect of "days of week".Results The single-pollutant model indicated that there were marked differences in association strength in these cities,among which the effect in Guangzhou was strongest.At multi-city level,a 10 μg/m3 increase of PM2.5 was associated with an increase of 0.315％ (95％CI:0.133％-0.497％) of daily cardiovascular disease mortality.From lag0 to lag2,the effect of PM2.5 on cardiovascular disease mortality decreased,while it was strongest on lag01.In the two-pollutant model,the estimated effect decreased in all the cities with the adjustments of SO2 or NO2.The insignificant combined results suggested that PM2.5 might have combined effect with other pollutants.Each 10 μg/m3 increase of PM2.5 was associated with increases of 0.371％ (95％CI:0.141％-0.600％) and 0.199％ (95％ CI:0.077％-0.321％) of cardiovascular disease mortality in males and females,respectively.The effect of PM2.5 on cardiovascular disease mortality increased with age and decreased with educational level,although the differences between different subgroups were insignificant.The dose-response relationship between PM2.5 and cardiovascular disease mortality was non-linear and non-threshold,with a steeper curve at lower concentrations.Conclusion The increases of PM2.5 concentration can result in the increase of daily cardiovascular mortality.
