Surveillance for viral diarrhea in sentinel hospitals in Henan province, 2013-2015
10.3760/cma.j.issn.0254-6450.2016.10.015
- VernacularTitle:河南省2013-2015年病毒性腹泻哨点医院监测结果与分析
- Author:
Jiayong ZHAO
1
;
Xiaojing SHEN
;
Baifan ZHANG
;
Zeqian WANG
;
Shengli XIA
;
Xueyong HUANG
;
Bianli XU
Author Information
1. 河南省疾病预防控制中心传染病防治所
- Keywords:
Diarrhea virus;
Infants;
Genotyping;
Epidemiological feature
- From:
Chinese Journal of Epidemiology
2016;37(10):1392-1396
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the infection status of human rotavirus,calicivirus,astrovirus and enteric adenovirus in children aged ＜5 years in disease surveillance areas in Henan province from 2013 to 2015.Methods A total of 880 stool samples were collected from four sentinel hospitals and group A rotavirus was detected by ELISA and group A rotavirus G/P genotyping was performed with nested multiplex RT-PCR,while rotavirus (group B,C),calicivirus and astrovirus were detected by two-step multiplex RT-PCR and adenovirus were detected by PCR.The epidemiological data of positive cases were statistically analyzed.Results A total of 594 positive samples were detected,including 24 mixed infection samples,370 rotavirus positive samples (42.0％);162 calicivirus positive samples (18.4％);69 astrovirus positive samples (7.8％) and 17 enteric adenovirus positive samples (1.9％).The overall positive rate of four viruses was significantly higher in urban area than in rural area,but the positive rate of rotavirus was higher in males than in females and in younger age group than in older age group.G9P [8] was the major genotype of group A rotavirus,there were two seasonal infection peaks in autumn and spring.Norovirus Ⅱ was the predominant type of calicivirus and the infection peak was in spring.Viral diarrhea cases were distributed in different age groups,mainly in age groups 0-12 months (rotavirus) and 3-5 years (calicivirus).The main clinical symptoms included fever,diarrhea and vomiting.The etiological characteristics differed with gender and area.Conclusions The infection rate of diarrheal viruses was higher in young children ＜5 years old in disease surveillance areas.The epidemiological and clinical features varied with the type of pathogen.
