Prenatal exposure to outdoor air pollution and preterm birth: a Meta-analysis
10.3760/cma.j.issn.0254-6450.2016.06.028
- VernacularTitle:孕期室外空气污染与早产关系的Meta分析
- Author:
Yu CHEN
1
;
Baibing MI
;
Yaling ZHAO
;
Jiaomei YANG
;
Yali TAO
;
Hong YAN
Author Information
1. 710061,西安交通大学医学部公共卫生学系流行病与卫生统计教研室
- Keywords:
Air pollution;
Preterm birth;
Periods of exposure;
Meta-analysis
- From:Chinese Journal of Epidemiology
2016;37(6):880-885
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the association between exposure to prenatal outdoor air pollution and preterm birth to provide evidence in setting up programs for prevention on premature birth.Methods Case-control studies regarding association between pregnant exposure to outdoor air pollution and preterm birth were collected.Data were analyzed with Stata 12.0.Results Ten articles including 48 556 cases and 548 495 controls were qualified for inclusion.Results from Meta-analyses showed pooled ORs for exposure to NO2,PM10,CO,PM2.5,and NO during the entire pregnancy were 0.960 (95％CI:0.935-0.985),1.068 (95％CI:1.035-1.103),1.122 (95％CI:1.078-1.168),1.110 (95％ CI:1.043-1.181) and 0.994 (95％ CI:0.973-1.016).Association between air pollution and preterm birth varied with the periods of exposure.Pooled ORs for NO2,PM10 and SO2 exposure during the first trimester were 1.117 (95％CI:1.052-1.186),0.968 (95％CI:0.812-1.153) and 1.258 (95％CI:0.758-2.089).Pooled ORs for NO2,PM10,SO2 exposure during the second trimester were 1.000 (95％ CI:0.982-1.019),1.127 (95％ CI:0.896-1.416) and 0.977 (95％CI:0.711-1.342).Pooled ORs for NO2,PM10,SO2 exposure during the third trimester were 1.006 (95％CI:1.002-1.010),1.053 (95％CI:0.973-1.139) and 1.003 (95％CI:1.000-1.006).Conclusion Exposures to PM10,CO and PM2.5 during the entire pregnancy,to NO2 during the first trimester,or to NO2 and SO2 during the third trimester were associated with preterm births.
