Meta-analysis on epidemiology of iatrogenic-borne methicillin-resistant Staphylococcus aureus
10.3760/cma.j.issn.0254-6450.2016.02.025
- VernacularTitle:我国医院中社区获得性耐甲氧西林金黄色葡萄球菌流行情况的Meta分析
- Author:
Yiqing ZHU
1
;
Baoli CHEN
;
Zhenwang BI
;
Zengqiang KOU
;
Bin HU
;
Ming FANG
;
Zhenqiang BI
Author Information
1. 山东大学公共卫生学院
- Keywords:
Methicillin-resistant Staphylococcus aureus;
Community acquired infection;
Nosocomial infection;
Panton-valentine leucocidin;
Drug resistance
- From:
Chinese Journal of Epidemiology
2016;37(2):273-280
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the molecular-biologic characteristics and epidemiological status of iatrogenic related Community-acquired methicillin-resistant Staphylococcus (S.) aureus (CA-MRSA) in China through Meta-analysis.Methods Data through systematic searching for peer-reviewed articles published before December 3rd,2015 from 4 main electronic databases including China National Knowledge Infrastructure (CNKI),Wanfang Data,PubMed and Web of Science Core Collection was collected,for this Meta-analysis.PRISMA guidelines were followed and the proportion of MRSA,CA-MRSA,hospital-acquired MRSA (HA-MRSA) and panton-valentine leucocidin (PVL) gene in certain populations were quantitatively analyzed by Stata 13.0 software.Results Average proportion of CA-MRSA from S.aureus was 12％ (95％CI:8％-16％).CA-MRSA in MRSA was 18％ (95％CI:12％-24％).42.1％ (95％CI:20.4％-63.7％) of the CA-MRSA carried a PVL gene,and the number was higher than general MRSA (t =-2.99,P=0.011).Conclusion CA-MRSA was in lower proportion than HA-MRSA,both seen in general MRSA and in S.aureu.s,but under higher proportion of carrying the PVL gene.Transmission of CA-MRSA could be prevented within the general population through conducting effective surveillances and preventive programs.
