Burden of colorectal cancer in China
10.3760/cma.j.issn.0254-6450.2015.07.010
- VernacularTitle:中国人群结直肠癌疾病负担分析
- Author:
Yue ZHANG
1
;
Jufang SHI
;
Huiyao HUANG
;
Jiansong REN
;
Ni LI
;
Min DAI
Author Information
1. 100021,北京协和医学院中国医学科学院肿瘤医院全国肿瘤防治研究办公室
- Keywords:
Colorectal neoplasms;
Incidence;
Mortality;
Burden of disease
- From:Chinese Journal of Epidemiology
2015;(7):709-714
- CountryChina
- Language:Chinese
-
Abstract:
Objective To understand the incidence and mortality of colorectal cancer in China. Methods The data from GLOBOCAN 2012,Chinese Cancer Registry Annual Report 2012, Cancer Incidence in Five Continents(CI5),the Three National Death Cause Surveys in China and WHO Mortality Database were used to learn about the incidence and mortality of colorectal cancer and related trends in China. Results It was estimated by GLOBOCAN 2012 that in 2012 the age-standardized incidence of colorectal cancer in China was 16.9 per 100 000 in males and 11.6 per 100 000 in females,and the age-standardized mortality was 9.0 per 100 000 in males and 6.1 per 100 000 in females. GLOBOCAN 2012 estimated that colorectal cancer incidence and mortality would increase with the level of human development index. China’s human development level was high, suggesting that the burden of colorectal cancer would be more serious in China with the development of social economy. The data from CI5 VolumeⅣand GLOBOCAN 2012 indicated that the incidence of colorectal cancer began to increase obviously at age of 50 years in China. Chinese Cancer Registry Annual Report 2012 showed that the incidence and mortality of colorectal cancer in urban population were two times higher than those in rural population in 2009,the proportions of colon cancer among colorectal and anus cancers,which was 49.0% in males and 54.2% in females,53.4% in urban population and 41.7%in rural population. CI5 VolumesⅣ-Ⅹshowed that colon cancer and rectum and anus cancer incidence in Shanghai for both males and females were increasing during the period 1973-2007. The percentage change in colon cancer and rectum and anus cancer incidence between 1973-1977 and 2003-2007 increased by 138.8%and 31.1%in males,146.7%and 49.1%in females, respectively. The data from the Three National Death Cause Surveys showed that the crude mortality of colorectal cancer increased by 77.9%form mid 1970’s(1973-1975)to mid 2000’s(2004-2005). WHO Mortality Database showed that average annual percentage change(AAPC)of age-standardized colorectal cancer mortality increased by 0.7%(P<0.05) from 1987 to 2000. Conclusion More attention should be paid to the prevention and control of colorectal cancer in urban area and in male population in China. Similar to the western countries,the burden of colorectal cancer in China would continue to become serious if no population based prevention and control programs are conducted.
