Association between serum uric acid and fasting plasma glucose in middle and elderly Chinese
10.3760/cma.j.issn.0254-6450.2014.10.018
- VernacularTitle:中老年人血尿酸与空腹血糖的相关性分析
- Author:
Yongjie YU
1
;
Chaoqiang JIANG
;
Yali JIN
;
Lin XU
;
Bin LIU
;
Weisen ZHANG
;
Karkeung CHENG
;
Taihing LAM
Author Information
1. 510620,广州医科大学附属市十二人民医院
- Keywords:
Hyperuricemia;
Fasting plasma glucose;
Serum uric acid;
Middle and elderly Chinese
- From:
Chinese Journal of Epidemiology
2014;(10):1155-1159
- CountryChina
- Language:Chinese
-
Abstract:
Objective To examine the association of fasting plasma glucose (FPG) and serum uric acid (SUA) in middle and elderly Chinese. Methods 10 413 Guangzhou residents aged ≥50 were included in the present study. Information on personal history,physical examination and biochemical parameters were collected. Subjects were grouped by the FPG level,association between FPG and SUA. Levels of hyperuricemia(HUA)were evaluated. Results The SUA levels and the incidence of HUA showed trends of increasing,with the increasing FPG levels in women,with statistically significant differences seen among all the FPG groups(P value for trend<0.05). While the statistical differences of SUA levels and the incidence rates of HUA among diabetes group(DM group)and impaired fasting glucose(IFG)groups were non-significant(P>0.05)but it was higher than normal FPG group in men (P<0.05). Logistic regression models were built between various FPG groups and HUA. After adjusting for age,smoking status,drinking status,physical activity, hypertension,body mass index and the levels of triglyceride and creatin. When compared to the normal FPG group,the risk of women suffering from HUA increased by 40%(95%CI:1.19-1.64) under the FPG in the range of 6.1-6.9 mmol/L. Compared to those non-diabetic individuals,the risk of diabetic patients suffering from HUA also increased by 44%(95%CI:1.15-1.79) in women. However,the risk of suffering from HUA did not relate to the increase of FPG in men. Conclusion The SUA level and the incidence of HUA tended to increase along with the increasing levels of FPG in middle and elderly Chinese women and the increase of FPG might also increase the risk of HUA,but not in men.
