Evaluation on the hepatitis A vaccine in preventing hepatitis A infection in Tianjin,from 2000 to 2011
10.3760/cma.j.issn.0254-6450.2014.10.011
- VernacularTitle:天津市2000-2011年甲型肝炎免疫控制效果评价
- Author:
Zhilun ZHANG
1
;
Xiangjun ZHU
;
Yaxing DING
;
Zhigang GAO
;
Yongcheng LI
;
Ailan SHAN
;
Yong LIU
;
Weidong XIA
Author Information
1. 300011天津市疾病预防控制中心
- Keywords:
Hepatitis A;
Immunization strategies;
Vaccination;
Evaluation studies
- From:
Chinese Journal of Epidemiology
2014;(10):1127-1130
- CountryChina
- Language:Chinese
-
Abstract:
Objective Hepatitis A immunization strategies were carried out in 2001 in Tianjin. We wanted to evaluate the effectiveness of the strategies related to hepatitis A control programs and to provide the basis for further modification of the strategies. Methods Descriptive epidemiology study was used to analyze the hepatitis A epidemic situation in 2000-2011 in Tianjin and to evaluate the disease reporting system. Hepatitis A vaccine coverage of target population and serum epidemiological study were carried out in 1999,2005 and 2010 to check on the hepatitis A antibody levels so as to evaluate the immuno-barrier condition in the normal population. Cox-Stuart test was used to analyze the epidemic trend of hepatitis A and other intestinal infectious diseases in Tianjin. Results The incidence rate of hepatitis A decreased from 2.89/100 000 in 2000 to 0.12/100 000 in 2011,and the percentage of hepatitis A in all types of viral hepatitis decreased from 8.02%in 2000 to 0.48% in 2011 in Tianjin. The positive rates of hepatitis A antibody also increased in the residents. Conclusion The hepatitis A vaccination program was successful in the programs on prevention and control of hepatitis A in Tianjin,China.
