Cost-effectiveness analysis of hepatitis B vaccination in People's Liberation Army
10.3760/j.issn:0254-6450.2001.02.019
- VernacularTitle:部队乙型肝炎疫苗预防接种的成本-效果分析
- Author:
Rong HU
1
;
Wuchun CAO
;
Xitan ZHANG
Author Information
1. the Second Military Medical University
- From:
Chinese Journal of Epidemiology
2001;22(2):142-145
- CountryChina
- Language:Chinese
-
Abstract:
Objective To select an optimal vaccination approach and provide basis for decision-making on the control of hepatitis B infection in PLA. Methods Decision trees were constructed. The yearly new infection rate in susceptible cohort, using a catalytic model, was estimated. Disability-adjusted life year (DALY) was used to assess the effectiveness. Incremental cost-effectiveness ratio (CER) was then calculated. Results Compared with no vaccination, DALY of immediate vaccination and vaccination after screening were 61.89 and 57.18 with CER 392.70 and 251.90 respectively. After weighting with actual age construction of PLA population, the CERs of vaccination after screening and immediate vaccination were 251.90 and 392.70 respectively. Conclusion The results indicated that screening followed by vaccination was superior to immediate vaccination approach. The younger the vaccination was carried out, the more cost-effective was shown by vaccination.
