Advances in expansion property of stent in vessels with different shapes
10.16156/j.1004-7220.2017.02.015
- VernacularTitle:不同形状血管中医用支架扩张力学行为的研究进展
- Author:
Xiang SHEN
1
;
Yong-Quan DENG
;
Zhong-Min XIE
;
Song JI
Author Information
1. 江苏大学机械工程学院
- Keywords:
In-stent restenosis (ISR);
Vascular shape;
Stent expansion;
Multi-objective optimization design;
Biomechanics
- From:
Journal of Medical Biomechanics
2017;32(2):194-198
- CountryChina
- Language:Chinese
-
Abstract:
The implantation of an intravascular stent has become a widely used minimally invasive treatment for coronary heart diseases due to its minimal invasiveness and high efficiency.But the long-term outcomes are often compromised by in-stent restenosis (ISR),which severely restricts its practical effectiveness.In this paper,the formation mechanism of ISR was discussed,and the effects of mechanical environment on ISR were analyzed from the view of solid mechanics.The research progress of stent expansion in vessels with 4 different shapes,including straight vessel,tapered vessel,bifurcation vessel and curved vessel was reviewed.Moreover,the correlations between vessel stress and vessel shape change caused by stent expansion and ISR were reviewed.Finally,based on the influence of different vessel shapes on stent expansion,a multi-objective optimization design method was proposed to improve the stent expansion performance and reduce the occurrence of ISR.
