Study on Gastric Empty Disorder after the Gastric Ulcer Healing and Therapeutic Effect of Cisapride
- Author:
Kaifang ZOU
1
;
Shi LIU
;
Jinsong LIU
;
Yongge LIU
;
Xiaohua HOU
;
Cuiqiong YI
Author Information
1. Xiehe Hospital Tongji Medical University
- Keywords:
gastric ulcer;
gastric emptying;
cisapride
- From:
Journal of Huazhong University of Science and Technology (Medical Sciences)
2000;20(1):57-58
- CountryChina
- Language:Chinese
-
Abstract:
Gastric emptying time of liquid meal was detected by using ultrasonography in 28 gas tric ulcer patients with continual or recurrent dyspepsia symptoms after the ulcer healing. Sixteen out of 28 patients (57.1%) with a delay of gastric emptying time (T1/2) were randomly divided into two groups: 8 cases were treated with cisapride 5 mg three times a day and 8 cases with cis apride 10 mg three times a day respectively. The results showed that cisapride could relieve the symptoms with the effective rate being 68.8% in the two groups. T1/2 in the patients after treat ment with cisapride was significantly shorter than before treatment (P＜0.001). It was concluded that there is a delay of T1/2 in some patients with gastric ulcer healing. Cisapride could promote gastric empty of liquid meal and relieve the symptoms efficiently. The effect of lower dose of cis apride is similar to that of higher dose.
