Synthesis and preliminary identification of L-alanyl-L-glutamine dip eptide
10.3321/j.issn:1000-5404.2001.05.026
- VernacularTitle:L-丙氨酰-L-谷氨酰胺的合成及初步鉴定
- Author:
Yong-Xin LI
1
;
Jun QIN
;
Shu-Ming ZHAO
Author Information
1. Southwest Hospital, Third Military Medical University
- From:Journal of Third Military Medical University
2001;23(5):571-572
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the method of chemical synth esis of L-alanyl-L-glutamine dipeptide. Methods L-alanyl-L -glutamine dipeptide was prepared by condensation and ammoniation reaction of L -glutamine and 2-D-chloropropionyl chloride. The physico-chemical properties of this dipeptide were identified with melting point determination, amino acid analysis, elements analysis and MS and its purity was determined with HPLC. Results This dipeptide was confirmed good in quality by physico-chem ical determination. Conclusion Dipeptide synthetized by this me thod is simple, convenient and with good guality.
