Surgical management and its therapeutic effect of gunshot wounded femor al arteries immered in seawater in rabbits
10.3321/j.issn:1000-5404.2001.05.018
- VernacularTitle:兔股动脉火器伤海水浸泡后的外科处理及其疗效
- Author:
Peng LIU
1
;
Xue-Liang PENG
;
Jin-Cai LIU
;
Xi-Nan LAI
;
Liang-Chao ZHANG
;
Guo-Ping WU
;
Li-Li WANG
Author Information
1. Daping Hospital Third Military Medical University
- From:Journal of Third Military Medical University
2001;23(5):547-549
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the surgical management of a gun shot wound of blood vessels and immersied, and evaluate its primary effect. Methods 100 rabbits were divided randomly into simple wounded group(SWG,n=50) and seawater immersion group(SIG,n=50).F emoral arteries were impacted by 0.38 gram steel spheres with velocity of 600 ～800 meters per second fired by 7.62 mm rifle. Animals in SIG were immersed in artificial seawater (pH 8.2～8.4, salinity 25.4,temperature 21℃) for 60 min, o f which those in SWG were spared. Grossly injuried artery was excised and restor ation of blood flow was reconstructed by end-to-end anastomosis or reversed au togenous venous grafting or cryopreserved arterial allografting. At 24 h,7,1 4,21 days after operation, blood flow was examined by Doppler ultrasonic detecti on and part of anastomotic sites and graft were collected for pathological obser vation. Results In completely transected injury, the patency in SIG was 80.00%,while that in SWG was 86.67% in the first 3 weeks. In arterial c ontused injury ,patency in SIG was 86.67%,and that in SWG was 82.35% at the same time. Thrombosis occurred mostly in the first postoperative week. Atypical endo thelial cells were found at the anastomosis sites in the first postoperative week, and the anastomosis sites were lined with endothelium in 3 weeks postopera tively. Conclusion Early curative effect could be obtained. Whe n grossly injuried artery is excised and followed by a routine surgical procedur e in the treating gunshot wounds immersed in seawater.
