Effects of breast milk and some infant foods on the adhesion of entero-pathogenic Escherichia coli (EPEC) to Hela cells and intestinal mucosa
10.3321/j.issn:1000-5404.2001.04.037
- VernacularTitle:母乳及婴儿食品对致病性大肠杆菌粘附的影响
- Author:
Feng-Ying WANG
1
;
Yu-Mei WANG
;
Qing CHANG
;
Lu JIANG
;
Chang-Xu SHI
Author Information
1. Southwest Hospital Third Military Medical University
- From:Journal of Third Military Medical University
2001;23(4):478-480
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of breast milk and some other kinds of infant foods on the adhesion of EPEC to Hela cells and intestinal mucosa so as to understand the possible protective mechanism of breast-feeding in the intestine of infants. Methods The adhesion of EPEC to Hela cells and intestinal mucosa were examined by cell culture, bacterial adherence test, light and electron microscopy in the mediums that contain breast milk, cow's milk and formula milk or contain ecal filtrate of the infants fed by breast milk and formula milk respectively. Results Adhesive index for EPEC to Hela cells was significantly lower in the medium containing breast milk than in control and so did in the fecal medium containing breast fed infants than artificial feeding infants. Conclusion Breast milk may inhibit the adhesion of EPEC to infant intestine.