Observation on the subclasses of IgG and subsets of T cell in 120 patients with inflammatory polyps of large intestine
10.3321/j.issn:1000-5404.2001.04.034
- VernacularTitle:大肠炎性息肉120例T细胞亚群和IgG亚类水平观察
- Author:
Dai-Wen HE
1
;
Su-Ling HONG
Author Information
1. First Affiliated Hospital of Chongqing Medical University
- From:Journal of Third Military Medical University
2001;23(4):471-472
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the corelation between patient with inflammatory polyp of large intestine and the changes of immunologic function. Methods Polyps of large intestine were extirpated from 120 patients with fiberoptic colonoscope and the pathological changes were studies. IgG subclass and T cell subsets in the peripheral blood were determined by ELISA and IFA methods. Similar parameters were determined in 30 cases of chronic colitis as control. Results CD8 in patients were lower than that of the control and CD4/CD8 were increased compared with those in control. Conclusion Disorder of humoral and cellular immunity might play an important role on the pathogenesis of polyp of large intestine.
