Experimental study of interbody fusion using CFR/PEEK
10.3321/j.issn:0258-879X.2001.04.015
- VernacularTitle:碳纤维增强的聚醚醚酮复合材料椎体间植入的实验研究
- Author:
Zhi-Cai SHI
1
;
Jia-Shun LI
;
Lian-Shun JIA
;
Wen YUAN
;
Tie-Sheng HOU
;
Ming LI
;
Xiao-Dong ZHU
Author Information
1. Changhai Hospital Second Military Medical University
- From:
Academic Journal of Second Military Medical University
2001;22(4):340-342
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the biocompatibility of CFR/PEEK composite in bone tissue after implanted in lumbar intervertebral space and to evaluate its role in the interbody fusion compared to the allograft bone. Methods: Thirteen beagles were chosen among which 7 were implanted with the disk-like CFR/PEEK composite in the lumbar intervertebral space and the other 6 were implanted with allograft bone. X-ray, QCT and histological examination were employed at 6, 12 and 24 months postoperatively. Results: The X-ray results of fusion segment were in conformity with the QCT's as well as that of histological results. All animals obtained a complete fusion at 24 months. Histological examination revealed that the anterior soft tissue to the implant exhibited a nonspecific foreign body reaction with connective tissue embed the biomaterials. Carbon fragment were seen in the surrounding tissue and some of the debric were phagocytosed by foreign body giant cell. Histological examination of bone and material revealed that new bone grew along the hole of CFR/PEEK implant. Conclusion: CFR/PEEK has an excellent biocompatibility to bone tissue.
