Immunohistochemical detection of melatonin receptor subtype in the adrenal corte x of the human embryo
10.3321/j.issn:0258-879X.2001.01.006
- VernacularTitle:人胚胎肾上腺皮质褪黑素受体亚型蛋白的分布
- Author:
Zu-Qian LU
1
;
Zhi-Min LIU
;
Jin HE
;
Hui-Min LIU
;
Ying ZHAO
;
Shu-Xun PENG
Author Information
1. Changzheng Hosptial, Second Military Medical University
- From:
Academic Journal of Second Military Medical University
2001;22(1):18-20
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the potential role of me latonin in the adrenal cortex of human embryo. Methods:Specifi c melatonin receptors was localized and characterized in the adrenal cortex of h u man embryo by means of immunohistochemistry. Results: mt1 (Me l1a)and MT2 (Mel1b)subtype of melatonin receptors was principally localize d to cytoplasm in zona glomerulosa, fasciculata and reticularis. Conclu sion: It is possible that mt1 and MT2 subtype of melatonin receptors co-exist in the adrenal cortex of human embryo.