Lower fat and better quality diet therapy for children with pharmacoresistant epilepsy.
10.3345/kjp.2013.56.8.327
- Author:
Jung Rim YOON
1
;
Heung Dong KIM
;
Hoon Chul KANG
Author Information
1. Division of Pediatric Neurology, Department of Pediatrics, Pediatric Epilepsy Clinic, Epilepsy Research Institute, Severance Children's Hospital, Yonsei University College of Medicine, Seoul, Korea. hipo0207@yuhs.ac
- Publication Type:Review
- Keywords:
Ketogenic diet;
Atkins diet;
Low-glycemic index diet;
Polyunsaturated fatty acid;
Epilepsy
- MeSH:
Child;
Diet;
Diet, Carbohydrate-Restricted;
Diet, High-Fat;
Epilepsy;
Fatty Acids, Unsaturated;
Humans;
Ketogenic Diet
- From:Korean Journal of Pediatrics
2013;56(8):327-331
- CountryRepublic of Korea
- Language:English
-
Abstract:
The ketogenic diet (KD) is an established, effective, nonpharmacologic treatment for children with pharmacoresistant epilepsy. Although the KD is the most well-established dietary therapy for epilepsy, it is too restrictive and is associated with serious complications; therefore, alternative lower-fat diets, including a modified Atkins diet and low-glycemic index diet, have been developed. Recent ongoing clinical evidence suggests that other dietary therapies have an efficacy almost comparable to that of the KD. In addition, a diet rich in polyunsaturated fatty acids appears to increase the efficacy of diet therapy and reduce the complications of a high-fat diet. Here, we review the systematic information about lower-fat diets and better-quality dietary therapies and the current clinical status of each of these dietary approaches.