Factors Affecting Treatment Discontinuation and Treatment Outcome in Patients with Schizophrenia in Korea: 10-Year Follow-Up Study.
- Author:
Seung Ho JUNG
1
;
Won Hyung KIM
;
Hye Jin CHOI
;
Min Hee KANG
;
Jeong Seop LEE
;
Jae Nam BAE
;
Chul Eung KIM
Author Information
1. Department of Psychiatry, In-ha University College of Medicine, Incheon, Korea. kce320@inha.ac.kr
- Publication Type:Original Article
- Keywords:
Schizophrenia;
Long-term;
Follow-up;
Outcome;
Treatment;
Discontinuation
- MeSH:
Clozapine;
Employment;
Female;
Follow-Up Studies;
Humans;
Korea;
Medication Adherence;
Retention (Psychology);
Schizophrenia;
Treatment Outcome
- From:Psychiatry Investigation
2011;8(1):22-29
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: There have been few long-term studies that have assessed factors influencing treatment discontinuation and long-term outcome of schizophrenia in Korea. The present study aimed to evaluate factors affecting treatment discontinuation and treatment outcome, after 10 years, in patients with schizophrenia. METHODS: Among hospitalized patients between 1997 and 1999, 191 patients were given continuous follow-up service. We examined the clinical characteristics and outcome of patients who remained in treatment. Regression analyses were used to find any clinical factors affecting treatment discontinuation. RESULTS: One hundred thirty-three patients (71.12%) discontinued the treatment. The treatment retention group contained more female patients, paranoid-type patients, patients who had shown self-harming behavior, patients receiving clozapine, and patients with good medication compliance. The recovery rate was 25%. However, 42.3% did not have gainful employment. Further, most patients couldn't live independently. CONCLUSION: The results show the importance of gender, patient behavior, medication, and medication compliance in predicting treatment discontinuation in patients with schizophrenia.
