Toxic effect of silicone oil on optic nerve
10.3980/j.issn.1672-5123.2019.5.18
- VernacularTitle:硅油对视神经的毒性作用
- Author:
Jing Xu
1
,
2
Author Information
1. Department of Ophthalmology, the Tenth People'
2. s Hospital of Tongji University, Shanghai 200072, China
- Publication Type:Journal Article
- Keywords:
silicone oil;
physicochemical properties;
optic nerve;
toxic effects
- From:
International Eye Science
2019;19(5):787-790
- CountryChina
- Language:Chinese
-
Abstract:
Silicone oil has been used as a safe and effective long-term vitreous substitute(VS)for more than 50 years. Clinically, it is currently widely used in surgical patients with severe ocular trauma and various complex vitreoretinal diseases, which has improved the prognosis of some previously incurable eye diseases. A series of toxic effects caused by the long-term retention of silicone oil in the vitreous cavity have attracted great attention. Based on the physicochemical properties of silicone oil, this review will analyze and summarize the toxic effects of silicone oil on the optic nerve, as well as its mechanism.
- Full text:201905018.pdf