Observation of neuropsychological development status in children after surgical treatment of congenital heart diseases
10.3760/cma.j.issn.1001-4497.2018.11.011
- VernacularTitle:先天性心脏病患儿术后神经智力发育测试
- Author:
Shuantong LIN
1
;
Ying LIANG
;
Xiaolong WANG
;
Xinguang WEI
;
Jingxin YAO
;
Dianyuan LI
;
Hao ZHANG
;
Cun LONG
;
Fu-Qing JIANG
;
Yulong GUAN
Author Information
1. 100037,中国医学科学院 北京协和医学院 国家心血管病中心 心血管疾病国家重点实验室 阜外医院体外循环科
- Keywords:
Congenital heart diseases;
Child;
Neuropsychological development;
Cardiac surgery
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
2018;34(11):683-687
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe neuropsychological development status in children after surgical treatment of congenital heart diseases(CHDs)and analyze the risk factors. Methods 89 children who received outpatient review in Fuwai Hospital from September 2015 to March 2016 after surgical treatment of CHDs were recruited in this study and 90 normal children were recruited as the control group. The children with CHDs were divided into simple CHDs group(RACHS- 1 score≤2)and com-plex CHDs group(RACHS- 1 score≥3)according to RACHS- 1 classification. Neuropsychological development status was meas-ured according to pediatric-psychological mental test scale developed by Capital institute of pediatrics,Beijing and statistical a-nalysis was compared. Results The measurements of neuropsychological development showed the normal children behaved better than the children with CHDs(P < 0. 05). The simple CHDs group achieved better distribution of development quotient than complex CHDs group(P = 0. 032)and there was no difference between the normal control group and simple CHDs group (P = 0. 420). Multivariate regression analysis indicated that younger age at cardiac surgery,lower preoperative blood urea ni-trogen(BUN),higher preoperative creatinine(Cr)and prolonged duration of cardiopulmonary bypass(CPB)accounted for low-er scores in the test scale(P < 0. 05). Conclusion Distinct neuropsychological difficulties could be present especially in chil-dren with complex CHDs. Younger age at cardiac surgery,preoperative BUN,Cr and CPB duration were perioperative factors that were associated with long-time neuropsychological development.
