Pregnancy associated Sj(o)gren's syndrome characterized by hyperglobulinemia: a case report
10.3760/cma.j.issn.1007-9408.2019.01.012
- VernacularTitle:以高球蛋白血症为重要表现的妊娠合并干燥综合征一例
- Author:
Guixiu JIN
1
;
Cailing LU
;
Chenyun YAN
Author Information
1. 浙江省台州市第一人民医院产科 318020
- Keywords:
Pregnancy complications;
Sjogren's syndrome;
Globulins
- From:
Chinese Journal of Perinatal Medicine
2019;22(1):55-57
- CountryChina
- Language:Chinese
-
Abstract:
The diagnosis,treatment and pregnancy outcome of a case of pregnancy associated Sj(o)gren's syndrome characterized by hyperglobulinemia were reported here.The patient who had a history of repeated purpura and anemia was admitted at 26+4 weeks of gestation with premature rupture of membranes.Multiple prenatal examinations showed elevated globulin without any other symptoms such as dry mouth,dry eyes,etc.No relevant tests was offered to confirm the diagnosis before or during pregnancy.After admission,she was diagnosed as Sj(o)gren's syndrome through immunoelectrophoresis and autoimmune antibody test,and hydroxychloroquine was administered.The patient gave birth to a 870 g newborn baby at 27 weeks of gestation.The premature infant was transferred to the Neonatology Department and later discharged after 2.5 months of treatment.A 3-month postpartum follow-up revealed that the patient still suffered from hyperglobulinemia,abnormal erythrocyte sedimentation rate and rheumatoid factor level,therefore she continued oral hydroxychloroquine treatment and was regularly followed up.Clinicians should be alert to the possibility of Sj(o)gren's syndrome in gravidas with hyperglobulinemia.
