Neonatal Langerhans cell histiocytosis: a case report
10.3760/cma.j.issn.1007-9408.2018.12.008
- VernacularTitle:新生儿朗格汉斯细胞组织细胞增生症一例
- Author:
Wenqing KANG
1
;
Caijun WANG
;
Yaodong ZHANG
;
Dapeng LIU
;
Yingyuan WANG
;
Li SONG
Author Information
1. 450018,郑州大学附属儿童医院 河南省儿童医院 郑州儿童医院NICU
- Keywords:
Histiocytosis,langerhans-cell;
Infant,newborn;
Case reports
- From:
Chinese Journal of Perinatal Medicine
2018;21(12):830-833
- CountryChina
- Language:Chinese
-
Abstract:
We reported a case of neonatal Langerhans cell histiocytosis (LCH) with his clinical manifestations, examinations, diagnosis and treatment. This infant was hospitalized due to the rash and poor response. He was diagnosed as LCH after admission by imaging, skin biopsy and immunohistochemistry. The infant died because his parents refused all possible treatments. At the moment, no effective treatment is available for LCH patients, while the main managements are infection control and necessary supportive care. Pulmonary infections often contribute to the death of LCH patient and can aggravate the situation by stimulating histiocytic hyperplasia.
