Association between microalbuminuria and cardiovascular risk factors in general population
10.3760/cma.j.issn.1001-7097.2019.01.005
- VernacularTitle:普通人群微量白蛋白尿与心血管疾病危险因素的关系
- Author:
Jianwei XU
1
;
Jixiang MA
;
Xiaorong CHEN
;
Liuxia YAN
;
Xiaoning CAI
;
Jing WU
Author Information
1. 中国疾病预防控制中心慢性非传染性疾病预防控制中心
- Keywords:
Albuminuria;
Cardiovascular diseases;
Risk factors;
24-hour urine
- From:
Chinese Journal of Nephrology
2019;35(1):30-35
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the association between microalbuminuria and cardiovascular risk factors in a general Chinese population.Methods A multi-stage cluster randomized sampling method was used to select 2400 residents (18-69 years old) in four counties in Shandong and Jiangsu provinces in October 2013 to March 2014.24-hour MAU were measured for each subject.The prevalence of MAU in different groups was analyzed.The relationship between the aggregation of risk factors and MAU was analyzed.Logistic regression analysis was used to evaluate the association between MAU and cardiovascular risk factors.Results A total of 2265 subjects were included in the analysis.The prevalence of MAU was 8.96％ (203/2265,95％ CI:7.82-10.21).The prevalence of MAU in obesity,hypertension,diabetes,hypertriglyceridemia,and low HDL-C group were 14.65％ (63/430),12.53％ (104/830),20.22％ (36/178),15.57％ (64/411),11.99％ (53/442) respectively,which were significantly higher than the corresponding healthy population (all P ＜ 0.01).Multivariate logistic regression analysis showed that obesity,hypertension,diabetes,and hypertriglyceridemia were risk factors for MAU.The OR(95％ CI) values were 1.491(1.016-2.265),1.660(1.190-2.314),2.291 (1.494-3.515) and 1.734(1.205-2.495) respectively.With the increase in the number of influencing factors,urinary albumin levels and the prevalence of MAU all showed an upward trend.Conclusion MAU was associated with cardiovascular risk factors such as obesity,hypertension,diabetes,and hypertriglyceridemia.
