The effect of surgical resection on the prognosis of colorectal carcinoma with synchronous hepatic metastases
10.3760/cma.j.issn.1007-631X.2018.11.006
- VernacularTitle:手术治疗对于同时性结直肠癌肝转移预后的影响
- Author:
Shengyong ZHAI
1
;
Xiaojing SUN
;
Xiaodong ZHONG
;
Guopeng DENG
;
Jianjun QU
Author Information
1. 261041,山东省潍坊市人民医院肿瘤外科
- Keywords:
Colorectal neoplasms;
Metastasectomy;
Survival analysis
- From:
Chinese Journal of General Surgery
2018;33(11):915-919
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of surgical treatment on survival in colorectal carcinoma patients with synchronous hepatic metastasis.Methods The retrospective case-control study was done on 953 consecutive patients with synchronous colorectal hepatic metastasesl from January 2003 to December 2013.Results Median survival time (46.7 months)and 5-year survival rate (32％) for patients with resected hepatic metastases was significantly superior to that of with nonoperative treatment (17 months,4％).Expanded criteria for hepatic metastases resection raised resection rates (31％ vs.13.6％,P ＜0.05).For patients with resectable hepatic metastases,the inhospital cost for simultaneous resection group was lower than that in the staged resection group (36 698 vs.45 134 RMB,P ＜ 0.05).For patients of asymptomatic primary tumor with unresectable hepatic metastases,resection of the primary tumor was associated with an improved median survival (18.0 vs.15.0 months,P ＜ 0.05) Conclusions Expanding indications of hepatic metastases resection can improve survival in patients with synchronous colorectal hepatic metastases.Simultaneous resection of primary tumor and hepatic metastases were indicated in patients with resectable synchronous colorectal hepatic metastases.Resection of primary tumor was recommended for asymptomatic patients with unresectable hepatic metastases.
