BP180-related autoimmune blistering diseases
10.3760/cma.j.issn.0412-4030.2019.01.017
- VernacularTitle:BP180相关自身免疫性水疱病的研究进展
- Author:
Suo LI
1
;
Suying FENG
Author Information
1. 中国医学科学院北京协和医学院皮肤病医院皮肤科江苏省皮肤病与性病学重点实验室
- Keywords:
Pemphigoid,bullous;
Pemphigoid gestationis;
Pemphigoid,benign mucous membrane;
Linear IgA bullous dermatosis;
BP180
- From:Chinese Journal of Dermatology
2019;52(1):50-52
- CountryChina
- Language:Chinese
-
Abstract:
BP180-related autoimmune blistering diseases include bullous pemphigoid,lichen planus pemphigoides,linear IgA bullous dermatosis,pemphigoid gestationis and cicatricial pemphigoid.There are multiple autoantibody-reactive sites on the extracellular region of BP180.Current studies show that there is heterogeneity in the autoimmune blistering disease-related target sites on BP 180,and different clinical manifestations of the same disease are related to the heterogeneity of target sites.However,further studies and analysis are still needed for the mechanism of the heterogeneity.