Efficacy of chemical thoracic sympathetic nerve modulation combined with pulsed radiofrequency in treating upper limb postherpetic neuralgia
10.3760/cma.j.issn.0254-1416.2018.08.009
- VernacularTitle:化学性胸交感神经调制术联合脉冲射频术对上肢带状疱疹后遗神经痛的疗效
- Author:
Keyue XIE
1
;
Qianying LIU
;
Kang AN
;
Bing HUANG
;
Ming YAO
;
Yanbao SUN
;
Jianbing MA
;
Zefeng ZHU
Author Information
1. 314001,嘉兴学院附属第一医院麻醉与疼痛医学中心
- Keywords:
Neuralgia,postherpetic;
Limbs;
Sympathectomy,chemistry;
Catheter ablation
- From:
Chinese Journal of Anesthesiology
2018;38(8):929-932
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy of chemical thoracic sympathetic nerve modulation combined with pulsed radiofrequency in treating upper limb postherpetic neuralgia ( PHN). Methods Forty-two patients of both sexes with upper limb PHN, aged 48-75 yr, were divided into 2 groups ( n=21 each) using a random number table method: chemical thoracic sympathetic nerve modulation combined with pulsed radiofrequency group ( TSNM+PR group) and pulsed radiofrequency group ( PR group) . TSNM+PR group was treated using chemical thoracic sympathetic nerve modulation combined with pulsed radiofrequen-cy, and PR group received pulsed radiofrequency alone. The occurrence of treatment-related adverse reac-tions was recorded. Numeric rating scale scores were recorded preoperatively and at 1 day and 1 and 3 months after operation, and the efficacy was graded. The effective treatment and pain recurrence were re-corded 3 months after operation. Quantitative sensory nerve tests were performed to record the current per-ception threshold before operation and on 1 day, 1 month and 3 months after operation. Results Compared with PR group, numeric rating scale score was significantly decreased, the therapeutic effect was en-hanced, the rate of effective treatment was increased, the recurrence rate of pain was decreased at 1 and 3 months after surgery, the current perception threshold at 250 and 5 Hz on the ipsilateral side was increased at 1 and 3 months after surgery in TSNM+PR group ( P<0. 05) . No treatment-related adverse reactions were found in two groups. Conclusion Chemical thoracic sympathetic nerve modulation combined with pulsed radiofrequency provides reliable therapeutic effect and higher safety for upper limb PHN.
