Effect of ultrasound-guided stellate ganglion block on perioperative inflammatory responses and postoperative recovery of gastrointestinal function in patients undergoing gastrointestinal surgery
10.3760/cma.j.issn.0254-1416.2018.08.003
- VernacularTitle:超声引导下星状神经节阻滞对胃肠手术患者围术期炎症反应及术后胃肠功能恢复的影响
- Author:
Lihua CHU
1
;
Ya WANG
;
Shuijing WU
;
Hui YE
;
Hui LI
;
Yaping LU
;
Haihong WANG
;
Xiangming FANG
;
Guohao XIE
Author Information
1. 浙江大学医学院附属第一医院麻醉科
- Keywords:
Ultrasonography;
Stellate ganglion;
Nerve block;
Inflammation;
Gastrointesti-nal motility
- From:
Chinese Journal of Anesthesiology
2018;38(8):904-907
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of ultrasound-guided stellate ganglion block ( SGB) on perioperative inflammatory responses and postoperative recovery of gastrointestinal function in patients un-dergoing gastrointestinal surgery. Methods Fifty-five American Society of Anesthesiologists physical classⅠ-Ⅲpatients of both sexes, aged 18-64 yr, weighing 50-75 kg, undergoing elective gastrointestinal sur-gery, were divided into SGB group ( n=18) and control group ( C group, n=37) using a random number table method. Ultrasound-guided SGB was conducted with 0. 5％ ropivocaine 7 ml at the left C6 level in SGB group. The equal volume of normal saline was given under ultrasound guidance at the same site in C group. Peripheral venous blood samples were collected at 5 min before SGB and 2, 4 and 24 h after SGB for deter-mination of plasma tumor necrosis factor-α ( TNF-α) , interleukin ( IL)-1β and IL-6 concentrations by en-zyme-linked immunosorbent assay. The increased level of leukocyte count ( leukocyte count at 24 h after SGB-leukocyte count at 24 h before SGB) was recorded. The recovery time of bowel sounds and anal or sto-ma exhaust time were also recorded. Results Compared with C group, the concentrations of TNF-αat 2 h after SGB and IL-1βat 2, 4 and 24 h after SGB were significantly decreased, the increased level of leuko-cyte count was decreased, and the recovery time of bowel sounds and anal or stoma exhaust time were short-ened in SGB group ( P<0. 05) . Conclusion Ultrasound-guided SGB can reduce perioperative inflammato-ry responses and promote the recovery of postoperative gastrointestinal function in the patients undergoing gastrointestinal surgery.
