Myxoid Myofibromatosis-type Perivascular Myoma Showing Prominent Verocay Body-like Formation.
10.5021/ad.2000.12.4.295
- Author:
Kyoung Ae JANG
;
Se Jin AHN
;
Jee Ho CHOI
;
Yeon Soon LIM
;
Kyung Jeh SUNG
;
Kee Chan MOON
;
Jai Kyoung KOH
- Publication Type:Case Report
- Keywords:
Verocay body-like;
Perivascular myoma
- MeSH:
Actins;
Alcian Blue;
Desmin;
Diagnosis, Differential;
Endothelial Cells;
Factor VIII;
Forearm;
Histiocytoma, Benign Fibrous;
Humans;
Hydrogen-Ion Concentration;
Leiomyoma;
Middle Aged;
Myofibroblasts;
Myoma*;
Neoplasms, Muscle Tissue;
Neurilemmoma;
Neuroma;
S100 Proteins;
Vimentin
- From:Annals of Dermatology
2000;12(4):295-298
- CountryRepublic of Korea
- Language:English
-
Abstract:
Differential diagnoses showing Verocay body-like formation include schwannoma, palisading myofibroblastoma, palisading cutaneous fibrous histiocytoma, dermatofibroma with myofibroblastic differentiation, leiomyoma, palisaded encapsulated neuroma, and neuroma. A 60-year-old Korean man presented with a 10-year-history of an asymptomatic nodule on the right forearm. Histopathological examination revealed well-circumscribed multi-micronodules with prominent Verocay body-like formation consisted of spindle cells and extensive infiltrate of mutinous materials. The spindle cells were negative for S-100 protein and desmin, but positive for vimentin and a-smooth muscle actin by immunohistochemical staining. The micronodules were lined by CD34 and factor VIII positive endothelial cells. The mutinous materials were stained with alcian blue at pH 2.5, but not at pH 0.5. We diagnose it as myxoid myofibromatosis-type perivascular myoma showing Verocay body-like formation.
