Effects of percutaneous coronary intervention on life quality and cardiac events in elderly patients with stable angina caused by chronic coronary total occlusion
10.3760/cma.j.issn.0254-9026.2019.02.003
- VernacularTitle:经皮冠状动脉介入治疗对老年冠状动脉慢性完全闭塞所致稳定型心绞痛患者生活质量和心血管事件的影响
- Author:
Jiang LI
1
;
Wenxian LIU
;
Yanlong REN
;
Yunpeng KANG
Author Information
1. 首都医科大学附属北京安贞医院心内科 100029
- Keywords:
Radiology;
intervention;
Angina pectoris;
Life quality
- From:
Chinese Journal of Geriatrics
2019;38(2):124-127
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of percutaneous coronary intervention(PCI)on life quality and cardiac events in elderly patients with stable angina owing to chronic coronary total occlusion(CTO).Methods Patients with stable angina due to CTO hospitalized in Beijing Anzhen Hospital from January 2015 to January 2018 were consecutively recruited in this prospective study,and were randomly divided into the combined treatment group(n=44)and the control group (n=43).Patients in the combined treatment group were treated with PCI and optimal medical therapy,and those in the control group were treated with optimal medical therapy alone.Patients followed up for 6 months after treatment.Cardiac function,life quality(Seattle angina questionnaire,SAQ)and adverse cardiovascular events were compared before and after treatment.Results A total of 87 patients were involved,with a mean age of (69.5 ± 7.2) years.Basic characteristics,including age,sex ratio,previous history,left ventricular ejection fraction,coronary artery lesions and SAQ scores,were similar between the groups(P＞0.05).After a 6 month post treatment follow up,SAQ scores improved in all patients,compared with those before treatment(P＜0.05).Moreover,patients in the combined treatment group had higher SAQ scores on physical limitation(86.3 ± 11.6 vs.76.3 ± 21.3),angina stability(67.3 ±24.5 vs.57.3±21.2)and angina frequency(93.3±4.3 vs.86.4±8.3)than those in the control group (P ＜0.05).There was no significant difference in major adverse cardiovascular event rate between the groups[18.2％(8 cases) vs.16.3％(7 cases),X2 =0.055,P＞0.05].Conclusions Combined with optimal medical therapy,PCI can improve the life quality in elderly patients with stable angina due to CTO,but has no significant influence on the short-term major adverse cardiovascular event rate.
