Analysis of related factors for clinical characteristics and the outcome in centenarian hospitalized patients
10.3760/cma.j.issn.0254-9026.2019.01.002
- VernacularTitle:百岁老年住院患者临床特点及其转归的相关因素分析
- Author:
Yu WANG
1
;
Weiwei SONG
;
Xiaoli CHEN
;
Zhiyong WANG
;
Jian DAI
;
Xiaojun OUYANG
;
Lili LIU
;
Yu LIU
;
Peng ZHANG
;
Zhaoling GUO
;
Yunyan WEI
;
Jihai CHEN
;
Weiwei YUAN
;
Weihong ZHAO
;
Jianqing WU
;
Wei XU
Author Information
1. 南京医科大学第一附属医院老年医学科老年医学重点实验室 210029
- Keywords:
Centenarians;
Hospitalization;
Pneumonia
- From:
Chinese Journal of Geriatrics
2019;38(1):4-9
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the health status of centenarian hospitalized patients and analyze the risk factors for in-hospital death in Nanjing district.Methods All centenarians hospitalized patients who were discharged from wards of 10 upper first-class general hospitals in Nanjing district during the past five years were retrieved from their hospital information systems.Then,a retrospective study was performed on centenarians' data of general information,laboratory test results,Charlson comorbidity index (CCI),neutrophil to lymphocyte ratio (NLR) and shock index(SI),etc.were calculated and collected.Relevant risk factors for in-hospital death were analyzed by multivariate logistic regression analysis.Results A total of 156 patients aged 100 years and over,with an average age of (101.0±2.1)years,were enrolled during the past 5 years.The top 3 admitting diagnosis for the patients were pulmonary infection(30.1％,47/156 cases),coronary heart disease(10.9％,17/156 cases)and cerebrovascular disease(7.1％,11/156 cases).Fifty patients died during hospitalization,with a mortality of 32.1％ (50/156).Pneumonia was the most common admitting diagnosis(40.0％,20/50 case).Among causes of death,the combined admitting diagnosis with dementia,chronic renal insufficiency,one or more basic disease were significantly associated with death.There were statistically significant differences between bad vs.good vs.indifferent prognosis in heart rate,shock index,leukocyte count,neutrophil count,NLR,hemoglobin,albumin,albumin/globulin,fasting blood glucose,blood urea nitrogen,serum creatinine,C-reactive protein(CRP)and CCI levels.Multivariate logistic regression analysis suggested that NLR≥13.18,fasting blood glucose ≥7.56 mmol/L,blood urea nitrogen ≥20.74 mmol/L,CRP≥65 mg/L and CCI≥3 might be predictors for in-hospital death in the cohort(OR =48.91、3.43、1.22、6.55、1.55,all P＜0.05).Conclusions Pulmonary infection is the most common reason for admission and the cause of death in centenarian inpatients.Comorbidities increase the risk of death.To lower in-hospital mortality,CCI and other assessment indicators should be used to strengthen the comprehensive assessment and chronic disease management of hospitalized centenarians.Infectious diseases should be prevented beforehand.
