A Case of Acute Interstitial Nephritis and Myoglobinuria after Alcohol Drinking.
- Author:
Byoung Ju NA
1
;
Oh Young CHUNG
;
Hu Seok LEE
;
Han Sun CHO
;
Hyeon Joo JEONG
Author Information
1. Department of Internal Medicine, Korea Veterans Hospital, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Rhabdomyolysis;
Myogobinuria;
Acute renal failure;
Acute interstitial nephritis;
Alcohol
- MeSH:
Acute Kidney Injury;
Alcohol Drinking*;
Alcoholics;
Biopsy;
Diagnosis, Differential;
Female;
Humans;
Kidney;
Metabolism;
Middle Aged;
Muscle Cells;
Muscle, Skeletal;
Myoglobinuria*;
Nephritis, Interstitial*;
Plasma;
Rhabdomyolysis;
Seizures;
Water-Electrolyte Balance
- From:Korean Journal of Nephrology
1999;18(4):625-629
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Rhabdomyolysis is defined as skeletal muscle injury with release of muscle cell constituents into the plasma and may lead to acute renal failure secondary to myoglobinuria. The causes of rhabdomyolysis is diverse:alcohol abuse, primary muscle disease, disturbance of muscle metabolism, sustained seizure, infection, drugs, tox ins, trauma, severe exercise, CO intoxication etc. Rhabdomyolysis may cause acute derangement in electrolyte balance and death. It should be diagnosed earlier and managed properly. We experienced a 49 year-old woman developed acute renal failure and myoglobinuria after alcohol drinking. A kidney biopsy revealed acute interstitial nephritis. In the presence of otherwise unexplained acute renal failure in alcoholic patients, rhabdomyolysis should be considered in the differential diagnosis.
