A Case of Nephrotic Syndrome Associated with Total Hydatidiform Mole.
- Author:
Hee Joong KIM
1
;
Yong Eun KWON
;
Sang Jun YOUN
;
Hyun Hwa SOHN
;
Jong O KIM
;
Sung Chul LIM
;
Jong Hoon CHUNG
Author Information
1. Department of Internal Medicine, Chosun University Medical School, Kwangju, Korea.
- Publication Type:Case Report
- Keywords:
FSGS;
Total hydatidiform mole;
Nephrotic syndrome
- MeSH:
Biopsy;
Edema;
Female;
Glomerulosclerosis, Focal Segmental;
Humans;
Hydatidiform Mole*;
Molar;
Nephrotic Syndrome*;
Pregnancy;
Uterus
- From:Korean Journal of Nephrology
1999;18(4):644-647
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A case study and review of nephrotic syndrome associated with a total Hydatidiform mole in 54- year-old female is presented. She has generalized edema, nephrotic range proteinuria(8.05gm/day), hypoalbuminemia(2.5g/dl) and high serum level of beta- hCG(200,000IU/L). Radiological investigations showed a 16-cm sized heterogenous enhanced mass in the uterus. A renal biopsy performed before evacuation of H-mole showed a focal segmental glomerulosclerosis. The complete remission of symptoms and signs of the nephrotic syndrom after evacuation of a molar tissue was achieved. A review of the literature revealed that this patient appears to be the first case of the FSGS with nephrotic syndrome associated with a total mole that remitted completely after the mole evacuation.