A Case of Stiff-Man Syndrome Associated with Panhypopituitarism.
- Author:
Kwng Soo KIM
1
;
Kyung Mu YOO
;
Joong Kyu KIM
Author Information
1. Department of Neurology, General Surgery Kosin Medeical College, Korea.
- Publication Type:Brief Communication
- MeSH:
Autoimmune Diseases;
Clonazepam;
Diazepam;
Extremities;
Female;
Humans;
Middle Aged;
Muscles;
Spasm;
Stiff-Person Syndrome*
- From:Journal of the Korean Neurological Association
1995;13(2):390-396
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Stiff-man syndrome is a rare disorder characterized by intermittent spasms and stiffness of the axial and limb muscles, associated with an electromyographic pattern of continuous motor unit activity in affected muscles. The cause of this disorder is unknown, but it has been associated with autoimmune disease and with endocrine disorder. We present a 49 year old female patient with clinical and electrophysiologic features of stiff-man syndrome and postoperative panhypopituitarism, whose muscle stiffness and spasm resolved with diazepam, clonazepam and prednisolonereplacement therapy.