Clinical outcomes of preoperative endoscopic nasobiliary drainage versus percutaneous transhepatic biliary drainage for patients with perihilar cholangiocarcinoma
10.3760/cma.j.issn.1007-8118.2018.12.006
- VernacularTitle:肝门部胆管癌患者术前经内镜鼻胆管与经皮经肝穿刺引流的效果比较
- Author:
Xiaoyuan CHEN
1
;
Liang MAO
;
Tie ZHOU
;
Yinyin FAN
;
Jing ZHANG
;
Min XIE
;
Yudong QIU
Author Information
1. 南京医科大学鼓楼临床医学院肝胆胰外科
- Keywords:
Perihilar cholangiocarcinoma;
Biliary drainage;
Endoscopic nasobiliary drainage;
Percutaneous transhepatic biliary drainage
- From:
Chinese Journal of Hepatobiliary Surgery
2018;24(12):812-817
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the clinical outcomes of endoscopic nasobiliary drainage (ENBD) versus percutaneous transhepatic biliary drainage (PTBD) in patients with perihilar cholangiocarcinoma.Methods This retrospective case-control study was conducted on 55 patients with perihilar cholangiocarcinoma who were treated by of hepatobiliary and pancreatic surgeons at the Nanjing Drum Tower Hospital between December 2010 and August 2017.Results There was no significant difference in the effectiveness of the two drainage methods (P＞0.05).Morbidity after drainage was significantly higher in the ENBD group than the PTBD group (86.7％ vs 28.0％,P＜0.05).24 patients in the ENBD group developed postERCP pancreatic complications which included hyperamylasemia (n =20) and pancreatitis (n =4).All these patients responded well to conservative treatment.A patient in the PTBD group developed catheter tract tumor implantation.There were no significant differences in the surgical outcomes and in the different Clavien-Dindo grades of complications (P＞0.05).Abdominal infection after surgery was more common in the PTBD group than the ENBD group (64.3％ vs 26.3％,P＜0.05).Conclusion As PTBD caused catheter tract tumor implantation and increased the incidence of abdominal infection after surgery,ENBD was recommended for patients with perihilar cholangiocarcinoma treated in a tertiary medical center.
