Correlation between ultrasonographic scoring system and pathological grading of the salivary glands in primary Sj(o)gren's syndrome
10.3760/cma.j.issn.1007-7480.2018.10.007
- VernacularTitle:原发性干燥综合征患者涎腺超声评分与唇腺病理分级的相关性研究
- Author:
Jixuan MIAO
1
;
YC ZHANG
;
Qin XUE
;
Dazhong ZOU
;
Jing HU
;
Ke ZHAO
Author Information
1. 215004,苏州大学附属第二医院超声中心
- Keywords:
Sjogren's syndrome;
Salivary glands;
Ultrasonography;
Biopsy
- From:
Chinese Journal of Rheumatology
2018;22(10):680-683,后插1
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation and diagnostic value between ultrasonographic scoring system and pathological grading of the salivary glands in primary Sj(o)gren's syndrome (pSS).Methods Fifty-seven patients with a suspected diagnosis of pSS were examined by ultrasonography and salivary gland biopsy.The ultrasound imaging of the salivary glands were analyzed and graded according to a 5-point (0-4)ultrasonographic scoring system.The results of salivary gland biopsy were graded according to the degree of lymphocytic infiltration.The receiver operating curve (ROC) was drawn and the area under curve (AUC) was calculated to test the diagnostic performance of the two methods.Spearman rank correlation analysis was used to compare the correlation between the two methods.Results Among the 57 patients,a definite diagnosis of pSS was established in 39 patients.The sensitivity,specificity and AUC of the ultrasonographic scoring system were 87.2％,77.8％ and 0.893 respectively,the sensitivity,specificity,and AUC of the salivary gland biopsy were 74.4％,88.9％ and 0.870 respectively.The ultrasonographic scoring system and grading of salivary gland biopsy showed a significant positive correlation (r=0.755,P＜0.01).Conclusion There is a good consistency between the u1ltrasonographic scoring system and the grading of salivary gland biopsy.As the diagrnostic value of the two methods are similar,ultrasonography reaches great diagnostic efficiency in pSS.
