Clinical experience of using continuous renal replacement therapy combined with hemoperfusion successfully saving patients with severe aconitine poisoning
10.3969/j.issn.1008-9691.2018.06.024
- VernacularTitle:连续性肾脏替代治疗联合血液灌流成功救治重度乌头碱中毒的经验体会
- Author:
Yanling CHEN
1
;
Liang LI
;
Feng SHEN
;
Wei LI
;
Yanlin XIAO
;
Guimei LI
;
Li CHEN
;
Wenyi YU
;
Ying PAN
;
Yue WU
Author Information
1. 贵州省第二人民医院重症医学科
- Keywords:
Continuous renal replacement therapy;
Hemoperfusion;
Aconitine poisoning
- From:
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care
2018;25(6):658-661
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the efficacy of continuous renal replacement therapy (CRRT) combined with hemoperfusion (HP) on patients with severe acute aconitine poisoning. Methods One patient suffered from severe acute aconitine poisoning was admitted into the Department of Critical Care Medicine of Affiliated Hospital of Guizhou Medical University, besides the gastric lavage and multi-organ supportive conventional therapies, CRRT combined with HP was given to the patient and his clinical data of life vital signs and other parameters were observed. Results After the patient underwent 4 episodes of CRRT (102 hours in total) and HP (8 hours in total) based on the conventional treatment, 4 days later, the disease situations were gradually stabilized, all of their parameters became gradually normal, the patient successfully weaned off from mechanical ventilation, the via mouth tracheal intubation was pulled out and the patient was transferred out of department of critical care medicine. Conclusion In the patient with acute aconitine poisoning, it is necessary to use CRRT combined with HP as early as possible, that can effectively eliminate the toxicant in the body and quickly correct the electrolytic and acid-base disturbances, so as the above combine method can improve the patient's prognosis and elevate the successful rescue rate.
