Progress in research on neurolymphomatosis
10.3969/j.issn.1000-8179.2018.22.085
- VernacularTitle:神经淋巴瘤病的研究进展
- Author:
Fan ZHIQIAO
1
,
2
;
Fan WENJING
;
Pan YAOZHU
Author Information
1. 甘肃中医药大学 兰州市730000
2. 中国人民解放军联勤保障部队第940医院
- Keywords:
neurolymphomatosis;
non-Hodgkin's lymphoma;
peripheral nerve;
nerve biopsy
- From:
Chinese Journal of Clinical Oncology
2018;45(22):1160-1163
- CountryChina
- Language:Chinese
-
Abstract:
Neurolymphomatosis is a malignant disease that occurs primary or secondary to non-Hodgkin's lymphoma and leukemia. It is mainly caused by lymphoma cells directly infiltrating peripheral nerves, and the incidence is low. The clinical manifestations vary ac-cording to the involved nerves and mainly present as decreased strength in the muscles innervated by the affected plexus/root. It is of-ten misdiagnosed as a polyneuropathy such as Guillain-Barre syndrome or chronic inflammatory demyelinating polyneuropathy. With combined treatment using immunoglobulins or steroids, the symptoms are temporarily improved but the disease still progresses rapid-ly, eventually requiring the attention of a physician. This paper will discuss clinical reports and research on neurolymphomatosis in re-cent years from the aspects of pathogenesis, clinical manifestations, differential diagnosis, diagnostic methods, treatment, and progno-sis, and will provide a theoretical basis for clinical diagnosis and treatment.
