Immunomodulatory drugs in type 1 diabetes mellitus: current status and future prospects
10.3760/cma.j.issn.1008-1372.2019.01.004
- VernacularTitle:免疫调节药物在1型糖尿病中的研究进展及应用前景
- Author:
Yangyang LI
1
,
2
;
Wei SHAO
;
Yu LIU
Author Information
1. 南京医科大学附属逸夫医院内分泌科 211100
2. 吉林大学第二医院内分泌科
- Keywords:
Diabetes mellitus;
type 1;
Insulin-secreting cells;
Immunomodulation;
Drug therapy;
combination
- From:
Journal of Chinese Physician
2019;21(1):11-15
- CountryChina
- Language:Chinese
-
Abstract:
The pathophysiological nature of type 1 diabetes mellitus (T1DM) as an autoimmune disease provides the basis for immunotherapy.As an important therapeutic approach,immunomodulatory drugs are promising in the protection of pancreatic β-cells by effecting at various stages of autoimmune progression.In this review,we summarize the recent advances of immunomodulatory drugs in the prevention and treatment of T1DM and propose future directions.