Effect of topical steroid treatment on children with severe phimosis
10.3760/cma.j.issn.1008-1372.2018.12.021
- VernacularTitle:局部外用糖皮质激素治疗小儿严重包茎的疗效观察
- Author:
Guanglun ZHOU
1
;
Jianchun YIN
;
Zhilin YANG
;
Man JIANG
;
Wanhua XU
Author Information
1. 518034,深圳市儿童医院泌尿外科
- Keywords:
Phimosis/DT;
Glucocorticoids/TU;
Liniments;
Child
- From:
Journal of Chinese Physician
2018;20(12):1841-1843
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical efficacy of 0.1% mometasone furoate cream in the treatment of phimosis in children.Methods A prospective study was carried out over two years period on an outpatient which basis on two groups of patients with severe phimosis.598 children with severe phimosis (Kikiros classification 4-5) aged from 2 years old to 11 years old and 8 months were selected.311 cases in the observation group and 287 cases in the control group.The observation group applied a steroid cream the foreskin twice a day for 4 weeks,and the control group used local handling of the foreskin twice a day for 4 weeks.The effects of the two groups after 2 and 4 weeks of treatment were compared.Results 29 cases in the observation group and 47 cases in the control group were loss of follow up.In the steroids group which including 282 patients,68.8% of patients (194 cases) showed a complete response (full retraction of the foreskin) to the therapy.The total efficiency rate of the 4 stage phimosis group is higher than the 5 grade phimosis group.Patients who had a history of balanoposthitis or urinary tract infection showed poorer improvement in preputial retraction.A total of 28 out of 240 patients (11.7%) in the control group showed a complete response to the therapy.The total efficiency rate of the observation group was significantly higher than the control group (x2 =173.121,P < 0.01).There were 4 cases of discomfort in the observation group and 6 cases of foreskin injured in the control group.Conclusions Topical application of 0.1% mometasone furoate cream in the treatment of severe phimosis in children is an effective,safe and simple non-invasive treatment with less adverse reactions.