Effects of oral-muscle biofeedback system training on rehabilitation of cognitive impairment in patients with obstructive sleep apnea after ischemic stroke
10.3760/cma.j.issn.1674-6554.2018.12.009
- VernacularTitle:口肌生物反馈系统训练对缺血性脑卒中后阻塞性睡眠呼吸暂停患者认知功能障碍康复的影响
- Author:
Jun HE
1
;
Tongbo LU
;
Jinmei ZHU
;
Xue QIAN
;
Suqin JIAO
;
Lixiang YAN
;
Yuquan DING
;
Lixia ZHANG
;
Tong WANG
Author Information
1. 常州市德安医院康复中心
- Keywords:
Oral muscle biofeedback system training;
Stroke;
Obstructive sleep apnea;
Cognitive dysfunction
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2018;27(12):1100-1104
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of oral-muscle biofeedback system training on the rehabilitation of cognitive dysfunction in patients with obstructive sleep apnea (OSA) after ischemic stroke.Methods A total of 60 cases of poststroke OSA patients with cognitive dysfunction admitted to the rehabilitation center of deAn hospital in changzhou city from June 2017 to March 2018 were selected.On the basis of routine rehabilitation treatment,the control group was given positive pressure ventilation treatment,and the observation group was given oral muscle biofeedback system training.The changes of polysomnography (PSG) parameters,Montreal cognitive assessment (MoCA) score,serum matrix metalloproteinase-9 (MMP-9) and plasma homcysteinemia (Hcy) expression levels in the two groups before and after treatment were compared.Results Apnea hypopnea index and maximum apnea time of the two groups were significantly decreased after treatment compared with those before treatment,and the lowest SpO2 and average SpO2 were significantly higher than those before treatment(P＜0.05).After treatment,MoCA total score and the dimensions score of patients in the observation group were significantly higher than those in the control group at the same time (P＜0.05).After treatment,the levels of Hcy((12.38±4.54) μmol/L) and MMP-9((124.52± 12.94) μg/L) in the observation group were significantly lower than those in the control group at the same time(Hcy(17.52±6.27) μmol/L,MMP-9(268.25±20.5 7)μg/L),and the difference was statistically significant (Hcy:t=3.637,P＜0.05;MMP-9:t =32.395,P＜0.05).Conclusions Positive pressure ventilation and oral muscle biofeedback system training have the same effect on OSA after stroke,but oral muscle biofeedback system training can also effectively improve patients' cognitive function.
