Relationship between sepsis-induced immunosuppression and multi-drugs resistant bacteria
10.3760/cma.j.issn.2095-4352.2018.11.017
- VernacularTitle:脓毒症免疫抑制与耐药菌产生的关系
- Author:
Gengxin CAI
1
;
Jingkun YE
;
Miaoyun WEN
Author Information
1. 华南理工大学附属广东省人民医院
- Keywords:
Sepsis;
Immunosuppression;
Secondary infections;
Multi-drugs resistance
- From:
Chinese Critical Care Medicine
2018;30(11):1095-1098
- CountryChina
- Language:Chinese
-
Abstract:
Sepsis is a life-threatening organ dysfunction caused by dysregulated host response to infection. Immunosuppression is an important factor of secondary infection in the late state of sepsis, including multi-drugs resistant bacteria, which ultimately leads to the death of patients. The aim of this article was to help clinical staffs better manage patients with sepsis, improve long-term survival rate of the patients, and reduce their re-hospitalization rate by reviewing the relationship between sepsis-induced immunosuppression and multi-drugs resistant bacteria through three aspects: the mechanism of sepsis-induced immunosuppression, the mechanism of antibiotic resistance and the relationship between sepsis-induced immunosuppression and secondary infections.
