Combined Phacoemulsification, Synechiolysis without Gonioprism Lens and Intracameral Tissue Plasminogen Activator Injection for Angle-Closure Glaucoma.
10.3341/jkos.2015.56.6.931
- Author:
Seok Ho CHO
1
;
Chang Won KEE
Author Information
1. Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. ckee@skku.edu
- Publication Type:Original Article
- Keywords:
Angle-closure glaucoma;
Fibrin reaction;
Synechiolysis;
Tissue plasminogen activator
- MeSH:
Cataract;
Fibrin;
Follow-Up Studies;
Glaucoma;
Glaucoma, Angle-Closure*;
Humans;
Hyphema;
Intraocular Pressure;
Phacoemulsification*;
Postoperative Complications;
Tissue Plasminogen Activator*
- From:Journal of the Korean Ophthalmological Society
2015;56(6):931-937
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: In this study we evaluated the safety and efficacy of combined phacoemulsification and synechiolysis without aid of gonioprism lens and intraoperative intracameral tissue plasminogen activator (tPA) injection for angle-closure glaucoma. METHODS: The method used in this study was synechiolysis with Kuglen hook without aid of gonioprism lens and intraoperative intracameral tPA injection following cataract surgery. RESULTS: A total of 20 patients with a mean age of 71.4 +/- 5.4 years were treated. Mean follow-up time was 31.3 +/- 24.3 months. Mean preoperative and last visit intraocular pressures (IOPs) were 21.70 +/- 9.50 mm Hg and 12.40 +/- 2.30 mm Hg, respectively (p < 0.0001). The mean number of glaucoma medications decreased from 2.40 to 0.30 (p < 0.0001). IOP was maintained below 16 mm Hg in all cases. No significant intraoperative and postoperative complications, hyphema, or fibrin reaction occurred. CONCLUSIONS: Combined phacoemulsification and peripheral anterior synechiolysis with Kuglen hook without aid of gonioprism lens and intraoperative intracameral tPA injection is an effective and safe surgical procedure.
