The geographical distribution characteristics of Brucella melitensis in Qinghai Province
10.3760/cma.j.issn.2095-4255.2018.12.005
- VernacularTitle:青海省羊种布鲁菌地理分布特点
- Author:
Guiying HU
1
;
Jianling WANG
;
Liqing XU
;
Hongmei XUE
;
Zhongzhi ZHAO
;
Jiquan LI
;
Guang TIAN
;
Yumin QIN
;
Junying MA
Author Information
1. 青海省地方病预防控制所布病科
- Keywords:
Brucella;
Molecular biology;
Geographic information systems
- From:
Chinese Journal of Endemiology
2018;37(12):969-971
- CountryChina
- Language:Chinese
-
Abstract:
Objective Molecular biological methods were used to classify and analyze the isolated Brucella strains,and to understand the geographical distribution characteristics,genetic types and regional distribution characteristics of Brucella in Qinghai Province.Methods Molecular biology typing of species of isolated Brucella strains in Qinghai was studied using Multiple Locus Variable-number tandem repeat Analysis (MLVA) technology.The classification results were described by geographical information system (GIS).Results There were 3 species Brucella melitensis,Brucella abortus,and Brucella suis among the 65 strains of Brucella in Qinghai.Brucella melitensis was the dominant species.The genotypes of MLVA were 42,43,47,28,36,112 and 6.The geographical distribution features showed that the 42 belonged to the evolutionary branches of A and B,which was widely distributed.The 43 of the C evolutionary branch and 47 of the E evolution branch were mainly in the hinterland of the Qinghai-Tibet Plateau.When searching in the Brucella2012 MLVA database,none of the genotypes obtained in this study were identical to those in the database.Conclusions The MLVA genotypes of Brucella are varied in Qinghai Tibet Plateau.They are widely distributed,completely different from those in other areas,and different genetic variations are found in different places.