Therapeutic effect of pedicled nasal septum mucosal flap on cerebrospinal fluid leakage in transsphenoidal approach
10.3760/cma.j.issn.1673-4904.2019.01.015
- VernacularTitle:带蒂鼻中隔黏膜瓣在经鼻蝶手术脑脊液漏中的疗效观察
- Author:
Hongzhu LYU
1
;
Jiyong LENG
;
Jia GUO
;
Xinmin WANG
;
Peiyu CONG
Author Information
1. 大连医科大学附属大连市中心医院神经外一科 116033
- Keywords:
Neuroendoscopes;
Cerebrospinal fluid leakage;
Pedicled nasal septum mucosal flap;
Skull base reconstruction
- From:
Chinese Journal of Postgraduates of Medicine
2019;42(1):57-60
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the therapeutic effect of pedicled nasal septum mucosal flap on high-flow cerebrospinal fluid leakage in transsphenoidal approach. Methods The clinical data of 31 patients with high-flow cerebrospinal fluid leakage during neuroendoscope transsphenoidal approach from January 2012 to April 2018 were analyzed retrospectively. Among them, skull base of 18 patients was reconstructed with pedicled nasal septum mucosal flap technique (observation group), and skull base of 13 patients was reconstructed with the'sandwich'method (control group). The postoperative cerebrospinal fluid leakage and complications were compared between 2 groups. Results Postoperative cerebrospinal fluid leakage occurred in 6 cases in control group, and 1 case in observation group, and there was statistical difference between 2 groups (P<0.05). Postoperative olfactory loss occurred in 2 cases in control group, and 3 cases in observation group, and there was no statistical difference between 2 groups (P>0.05). Conclusions Multilayer skull base reconstruction with pedicled nasal septum mucosal flap can significantly reduce the incidence of cerebrospinal fluid leakage after transsphenoidal tumor resection, and is a safe and reliable method to treat the high flow cerebrospinal fluid leakage in operation.
