Enhanced MR texture analysis in the differential diagnosis of solitary brain metastasis and high-grade glioma
10.3760/cma.j.issn.1673-4904.2018.12.017
- VernacularTitle:增强MR纹理分析在单发脑转移瘤与高级别胶质瘤中的鉴别价值
- Author:
Fei XIONG
1
;
Huibin TAN
;
Ying WANG
;
Ye WANG
;
Guiping SHENG
Author Information
1. 430070,解放军武汉总医院放射科
- Keywords:
Metastases;
Gliomas;
Magnetic resonance imaging;
Texture analysis
- From:
Chinese Journal of Postgraduates of Medicine
2018;41(12):1121-1124
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of enhanced MR texture analysis in the differential diagnosis of single brain metastasis (SBM) and high grade glioma (HGG). Methods The preoperative MRI images of 21 SBM and 23 HGG patients confirmed by pathology were retrospectively analyzed. The T1WI enhanced images were used for texture analysis to obtain the mean, median, entropy, skewness, kurtosis, heterogeneity and other parameters. An independent sample t-test or Mann-Whitney U test was used to statistically analyze the values of the parameters between the two groups, and ROC evaluation parameters were used to identify the diagnostic efficacy of SBM and HGG. Results There were significant differences in entropy and heterogeneity parameters between SBM and HGG: (4.838 ± 0.523 vs. 5.358 ± 0.449, 0.276 ± 0.066 vs. 0.331 ± 0.101), P＜0.05. When the cut-off value of entropy was 4.88, the sensitivity of differential diagnosis between SBM and HGG was 47.6%, specificity was 100.0%, and the area under ROC curve was the largest (0.745). Conclusions The entropy value and heterogeneity have certain value in distinguishing SBM and HGG in MRI texture analysis.
