ADC measurement in assessment of tumor grade and myometrial invasion of endometrial carcinoma
10.3969/j.issn.1002-1671.2018.12.019
- VernacularTitle:表观扩散系数值测量对子宫内膜癌组织学分级和肌层浸润深度的评估价值
- Author:
Jia LIU
1
;
Shijia WANG
;
Guofu ZHANG
;
Fenghua MA
;
Xiaomei TIAN
;
Dongyan WANG
;
Yanyu ZHANG
;
Shouxin GU
;
Minjie WU
Author Information
1. 复旦大学附属妇产科医院放射科
- Keywords:
endometrial carcinoma;
magnetic resonance imaging;
diffusion weighted imaging;
apparent diffusion coefficient
- From:
Journal of Practical Radiology
2018;34(12):1893-1897
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of the apparent diffusion coefficient (ADC)measurement in assessment of tumor grade and myometrial invasion of endometrial carcinoma (EC).Methods 80 EC patients and 28 cervical cancer patients with normal endometrium were studied retrospectively.1.5T conventional MRI and DWI (b=0,1 000 s/mm2)were performed,and ADC values were calculated by two radiologists.Statistical analyses were performed by using SPSS 19.0 and Medcalc software.Results The mean ADC values (×10-3mm2/s)were 0.851±0.131,0.752±0.099,0.681±0.089 for G1,G2 and G3 EC,respectively.Significant statistical differences were achieved for the three groups (G1 vs G2:P=0.005;G2 vs G3:P=0.03;G1 vs G3:P< 0.000 1).For the prediction of G3,the area under the curve (AUC)of 0.851 and the cut-off value of ≤0.742×10-3mm2/s were identified,with the sensitivity, specificity and accuracy of 88.24%,76.19% and 85%,respectively.Conclusion There are significant statistical differences between histologic grades of EC.ADC measurement may have the potential to select G3 EC patients.
