The value of IVIM-DWI and DTI in the diagnosis of invasive breast carcinoma of no special type
10.3969/j.issn.1002-1671.2018.12.014
- VernacularTitle:体素内不相干运动扩散加权成像及扩散张量成像对乳腺非特殊类型浸润性癌的诊断价值
- Author:
Lifang SI
1
;
Xiaojuan LIU
;
Kaiyan YANG
;
Li WANG
;
Yichen MA
;
Tao JIANG
Author Information
1. 首都医科大学附属北京朝阳医院放射科
- Keywords:
breast neoplasm;
diffusion weighted imaging;
magnetic resonance imaging
- From:
Journal of Practical Radiology
2018;34(12):1874-1877
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the value of IVIM-DWI and DTI parameters in quantitative analysis and differential diagnosis of invasive breast carcinoma of no special type(NST).Methods We retrospectively analyzed 60 patients (63 lesions)who underwent MR examination in our hospital and all lesions were verified by pathologic results.MR protocol included DCE-MRI,IVIM-DWI using 14b values and DTI.The ADC,ADCslow,ADCfast,f,λ1of lesions were measured and compared by two independent samples t test between the benign lesions and NST.Logistic regression analysis was made using ADC,ADCslow,f,λ1as predictors in detecting and differentiating the NST,ROC analysis was performed to compare diagnostic performance based on the area under the curve(AUC).Results The ADC,ADCslow,ADCfast,f andλ1of NST were (1.49±0.63)×10-3mm2/s,(1.32±0.49)×10-3mm2/s,(25.98±21.84)×10-3mm2/s,0.20±0.13 and (4.98±0.47)×10-3mm2/s,these values of benign lesions were (2.31±0.66)×10-3mm2/s,(2.24±0.65)×10-3mm2/s,(18.71± 12.26)×10-3mm2/s,0.33±0.15 and(5.59±0.59)×10-3mm2/s.All parameters except ADCfast(P=0.271)had significantly statistical differences (P<0.000 1)between NST and benign lesions.The regression model showed that ADCslowwas an independent predictor in NST’s detection.Conclusion The ADC,ADCslow,f andλ1is helpful for differentiation between NST and benign lesions.The regression model is most valuable in NST detection and ADCslowis the preferred index.
