Diagnostic value of multimodal MRI in patients with temporal lobe epilepsy caused by dual pathology
10.3969/j.issn.1002-1671.2018.12.003
- VernacularTitle:多模态MRI对双重病理所致颞叶癫痫的诊断价值
- Author:
Lina CHENG
1
;
Wensheng WANG
;
Shengwen GUO
;
Chunren LAI
;
Di ZHAO
;
Jun SHEN
Author Information
1. 中山大学孙逸仙纪念医院放射科
- Keywords:
temporal lobe epilepsy;
grey matter;
magnetic resonance imaging
- From:
Journal of Practical Radiology
2018;34(12):1835-1838
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the diagnostic value of multimodal MRI for dual pathology (DP)in temporal lobe epilepsy (TLE).Methods The methods of voxel based morphometry (VBM)and voxel based analysis (VBA)had been employed to study the difference between 36 patients (20 cases left group and 16 cases right group)with TLE caused by DP and 36 healthy subjects on the grey matter (GM)volume,exponential apparent diffusion coefficient (eADC)and cerebral blood flow (CBF)value.The corresponding statistical study had also been conducted.Results There were significant statistical differences (FDR correction,P=0.001)between healthy subj ects and patients on the GM volume,eADC and CBF value.Those values decreased with diseased laterality and wider range in functional imaging.These overlaying abnormal brain regions were located in the temporal pole (superior temporal gyrus), temporal pole (middle temporal gyrus),middle temporal gyrus,inferior temporal gyrus,fusiform gyrus,hippocampus and parahippocampal gyrus which represented in all examination results.Conclusion The combined findings of multimodal MRI can improve the localization ability of seizure focus in TLE,which caused by DP,before surgery.
