Progress of the study on cytosine arabinoside in the treatment of acute leukemia in children
10.3760/cma.j.issn.2095-428X.2014.03.002
- VernacularTitle:阿糖胞苷治疗儿童白血病研究进展
- Author:
Huijun ZHAO
1
Author Information
1. 上海交通大学医学院苏州九龙医院儿科
- Keywords:
Cytosine arabinoside;
Leukemia;
Metabolic key enzyme;
Long-term efficacy;
Adverse reaction
- From:
Chinese Journal of Applied Clinical Pediatrics
2014;29(3):165-167
- CountryChina
- Language:Chinese
-
Abstract:
Cytosine arabinoside (Ara-C) is one of the key chemotherapy drugs comprising all stages combined protocols during long-term chemotherapy for children with acute leukemias,which demonstrated its efficacy and safety.Along with the progress of basic and clinical researches,in Ara-C clinical dose and treatment,prevention of adverse reactions,relationship between the drug metabolism and long-term clinical results,and new nucleoside drugs have achieved remarkable results.This paper on the above fields of research,progress and trends,briefly summarized as follows.
