Hypothermia therapy and the neuroprotection of neonates with hypoxic-ischemic encephalopathy
10.3760/cma.j.issn.2095-428X.2014.02.002
- VernacularTitle:亚低温治疗与脑保护
- Author:
Chuanzhong YANG
1
;
Xiaoyu ZHU
Author Information
1. 南方医科大学深圳妇幼保健院新生儿科
- Keywords:
Hypothermia;
Hypoxic-ischemic encephalopathy;
Neuroprotection;
Infant,newborn
- From:
Chinese Journal of Applied Clinical Pediatrics
2014;29(2):86-89
- CountryChina
- Language:Chinese
-
Abstract:
Perinatal hypoxic-ischemic brain damage is still threatening the quality of the survivors.Immediate hypothermia on the basis of early multimodality therapy is a good therapy for newborn with hypoxic-ischemic encephalopathy(HIE).The neuroprotective effects of hypothermia therapy are noted at 18 months of age persist to childhood.This paper will discuss the neuroprotective mechanism of hypothermia for neonate HIE,the clinical application of cooling and the novel strategies of hypothermia plus adjuvant therapies.
